CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)

Vysis LSI ATM (11q22.3) SpectrumOrange Probe

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PRODUCT NAME UNIT SIZE ORDER NUMBER GTIN

 

This fluorescence in situ hybridization (FISH) probe is intended to detect deletion of the LSI ATM probe target sequence containing the ATM gene at chromosomal location 11q22.3.

The approximately 732 kb SpectrumOrange LSI ATM probe contains the complete ATM gene and is located at 11q22.3.

 

This probe set allows status assessment of the ATM gene region on chromosome 11q22.3. In a normal cell with two intact copies of the ATM gene region, a two orange signal pattern will be observed.

This probe set allows status assessment of the ATM gene region on chromosome 11q22.3. In an abnormal cell with a deletion in the ATM gene region, fewer than two orange signals will be observed.

Normal Hybridization: Result of the hybridization of the LSI ATM (11q22.3) Probe as observed in a normal interphase cell.

Abnormal Hybridization: Abnormal cell hybridized with the LSI ATM (11q22.3) Probe. The cell in this image shows the one orange signal pattern indicative of a deletion of one copy of the ATM gene region on chromosome 11q22.3.