OTHER CANCERS

Vysis LSI N-MYC SpectrumGreen/CEP 2 SpectrumOrange Probes

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PRODUCT NAME UNIT SIZE ORDER NUMBER GTIN


Vysis LSI N-MYC SpectrumGreen/CEP 2 SpectrumOrange Probes hybridize to the band region 2p24 (LSI N-MYC SG) and the alpha satellite region (CEP 2 SO) of human chromosome 2. The hybridized probe fluoresces with bright to moderate intensity both in interphase nuclei and on metaphase chromosomes.


In a normal cell with two intact copies of chromosome 2, two green and two orange signals will be observed. In an abnormal cell containing amplification of the N-MYC oncogene, greater than two green signals will be observed.

Abnormal Hybridization: An abnormal sample hybridized with the LSI N-MYC (2p24)/ CEP 2 (2p11.1-q11.1) Dual Color Probe showing a high level of amplification of the N-MYC oncogene.