Vysis LSI SS18 Break Apart FISH Probe Kit
For more information, contact Abbott.
For more information, contact Abbott.
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This fluorescence in situ hybridization (FISH) probe is intended to detect chromosome rearrangements involving the SS18 (SYT) gene located on chromosome 18q11.2
The Vysis SS18 Dual Color, Break Apart Rearrangement Probe consists of a mixture of 2 FISH DNA probes. The first probe, a ~650 kb probe labeled in SpectrumOrange, extends distally from the SS18 gene. The second probe labeled in SpectrumGreen lies 3′ or proximal to the SS18 gene and is 1044 kb in length.
In a normal cell that lacks a t(18q11.2) in the SS18 gene region, a two fusion signal pattern will be observed, reflecting the two intact copies of SS18.
In an abnormal cell with a simple t(18q11.2), a one fusion, one green and one orange signal pattern will be expected.
Normal Hybridization: Result of the hybridization of the Vysis LSI SS18 (18q11.2) Dual Color Break Apart Rearrangement Probe, showing the two fusion signal pattern as observed in normal interphase cells. (Photo courtesy of Arie Perrry, M.D., Washington University School of Medicine.)
Abnormal Hybridization: Abnormal cells hybridized with the Vysis LSI SS18 (18q11.2) Dual Color, Break Apart Rearrangement Probe. The cells in this image show the one fusion, one orange and one green signal pattern indicative of a rearrangement of one copy of the SS18 gene region. (Photo courtesy of Arie Perry, M.D., Washington University School of Medicine.)
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Please be aware that the website you have requested is intended for the residents of a particular country or countries, as noted on that site. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions.