Vysis LSI TOP2A / CEP 17 FISH Probe Kit
For more information, contact Abbott.
For more information, contact Abbott.
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The Vysis LSI TOP2A/CEP 17 FISH Probe Kit is intended to determine TOP2A and chromosome 17 copy numbers, and hence can distinguish TOP2A amplification and deletion from chromosome 17 aneusomy.
The Vysis LSI TOP2A SpectrumOrange/CEP 17 SpectrumGreen Probes vial contains a mixture of 2 probes. The TOP2A probe is a single approximately 166 kb unique sequence probe direct labeled in SpectrumOrange, that hybridizes to the 17q21-q22 region of chromosome 17 and includes the 30 kb topoisomerase II-α gene. The CEP 17 probe hybridizes to alpha satellite DNA on chromosome 17 (17p11.1-q11.1) and is directly labeled in SpectrumGreen. This probe set is premixed in hybridization buffer.
In a cell with the normal quantity (two copies) of the TOP2A gene, two orange signals will be observed. If amplification or deletion of the TOP2A gene has occured, more or less than two signals will be present.
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Please be aware that the website you have requested is intended for the residents of a particular country or countries, as noted on that site. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions.