Vysis LSI RUNX1 SpectrumGreen Probe

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The SpectrumGreen Vysis LSI RUNX1 fluorescence in situ hybridization (FISH) probe is targeted to the 21q22 region on chromosome 21. The probe is ~1.4 Mb in size and spans the entire RUNX1 gene. The hybridized probe fluoresces with moderate to bright intensity both in interphase nuclei and on metaphase chromosomes.

 

Two lymphocyte cells, one in interphase (upper left) next to chromosomes from a metaphase cell (lower right), that have been hybridized with the LSI ETV6/RUNX1 Dual Color Dual Fusion Probe. Both cells show the two orange (RUNX1), two green (ETV6) signal pattern.

A bone marrow cell in interphase hybridized with the LSI ETV6/RUNX1 Dual Color Dual Fusion Probe. The cell in this image shows the one orange (RUNX1), one green (ETV6), two fusion (der (12) and der (21)) signal pattern.