Vysis Prader-Willi/Angelman Region LSI SNRPN SpectrumOrange/CEP 15 SpectrumAqua/PML SpectrumGreen Probes

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PRODUCT NAME UNIT SIZE ORDER NUMBER GTIN


The SpectrumOrange SNRPN probe hybridizes to 15q11.2.  The probe is 125 kb in size and spans the SNRPN gene.  The CEP 15 probe is labeled in SpectrumAqua and hybridizes to the centromeric region of chromosome 15 and acts as a control probe. The PML SpectrumGreen probe hybridizes to the 15q22-24 region and is 180 kb in size.  The probe may be used with metaphase chromosomes or interphase nuclei.  The signals may also appear diffuse or split depending upon the condensation of the DNA and the relative distances between chromatids.  The hybridized probe fluoresces with moderate to bright intensity both in interphase nuclei and on metaphase chromosomes.