Vysis Smith-Magenis Region LSI SMS SpectrumOrange/RARA SpectrumGreen Probes

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Vysis Smith-Magenis Region LSI SMS SpectrumOrange/RARA SpectrumGreen Probes hybridize to band 17p11.2 (LSI SMS SpectrumOrange) and band 17q21 (LSI RARA SpectrumGreen). The LSI SMS probe contains sequence-tagged sites (STSs) for the gene FLII,TOP 3 and SHMT1. The hybridized probe fluoresces with moderate to bright intensity both in interphase nuclei and on metaphase chromosomes.


Metaphase spread containing one chromosome 17 with the SpectrumGreen SpectrumGreen the SpectrumOrange LSI SMS Probe signal. The normal chromosome 17 shows the presence of the SpectrumOrange LSI SMS Probe and the SpectrumGreen LSI RARA Control Probe.